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Dealing with a Diagnosis of Prostate Cancer

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Well obviously when patients are diagnosed with prostate cancer it’s a very, very significant thing in their lives and their whole family and I really understand what a big impact this makes to the patient and the family.

They’re often shocked and it’s very hard for them to come to grips with the initial diagnosis.

So I ensure that I have long consultations with them, we spend up to an hour at least on one and usually two occasions with them.

I encourage the family to come along and we have a long discussion.

I normally discuss the pros and cons of all the options.

First of all I explain the pathology, we go through the findings, the diagnosis, the grade, the stage.

I can then tell them roughly what the natural history of that disease is, if we do nothing or if they have treatment and then I discuss all the treatment options with them and I like to be able to offer all the treatments of prostate cancer (which I do in my practice) and I discuss the pros and cons of all these treatments.

So I will discuss observation or active surveillance with selective intervention.

I’ll discuss surgery in the form of open, laparoscopic surgery or robot-assisted surgery and radiotherapy in the form of external beam radiation, high dose rate bracchytherapy and seed therapy or low dose bracchytherapy.

I also discuss the experimental and emerging treatments of cryotherapy1 and high intensity focus ultrasound (HIFU)2 and finally we have a discussion about hormone therapy although that’s generally used in very elderly men or people who have evidence of spread elsewhere3.

So I discuss the pros and cons of all these treatments.

I discuss this with the patient.

We take into account issues that the patient has such as the size of the prostate, previous surgery and most importantly patient preference.

So patients we’ll give different waiting, to different potential side effects.

Some patients will want to have surgery to have the cancer removed, other patients would prefer not to have surgery and to have another form of treatment such as radiotherapy.

So it’s a long and complex discussion but I think it’s very, very important for patients to have this and generally it’s a decision that the patient makes but with my guidance.

We don’t expect them to be experts in prostate cancer straight away but they get a very good understanding and usually they make a very good and very well informed decision after they’ve got all the information.

Dealing with a Diagnosis of Prostate Cancer

A diagnosis of prostate cancer is significant for the patient and the whole family. Most patients are shocked and find it hard to take in at first. Dr Kooner’s approach is to make plenty of time for these consultations - typically at least an hour on one or two occasions - and family members are encouraged to come along.

What is discussed in the consultation

  1. The pathology - going through the biopsy findings, the grade and the stage of the cancer.
  2. Natural history - a realistic outline of what is likely to happen with no treatment, and with treatment.
  3. All treatment options, with the pros and cons of each.

Treatment options covered

  • Observation / active surveillance with selective intervention.
  • Surgery - open, laparoscopic, or robot-assisted.
  • Radiotherapy - external beam radiation, high dose rate brachytherapy, or seed (low dose rate) brachytherapy.
  • Experimental / emerging treatments such as cryotherapy1 and high-intensity focused ultrasound (HIFU).2
  • Hormone therapy, generally reserved for elderly patients or where there is evidence of spread.3

Dr Kooner offers all of these treatments in his own practice.

Making the decision

The decision takes into account the size of the prostate, any previous surgery, and - most importantly - patient preference. Different men weigh the possible side effects differently: some want the cancer physically removed with surgery, while others prefer to avoid an operation and choose radiotherapy.

It is a long and complex discussion, but an important one. The final decision is made by the patient, with Dr Kooner’s guidance. Patients aren’t expected to be experts overnight, but once they have all the information they are usually in a strong position to make a very well-informed decision.

References
  1. Cryotherapy for Primary Treatment of Prostate Cancer: Intermediate Term Results of a Prospective Study from a Single Institution - S. Alvarez RodrĂ­guez, F. Arias FĂșnez, C. Bueno Bravo, et al - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945790/
  2. High intensity focused ultrasound (HIFU) for prostate cancer - Cancer Research UK - https://www.cancerresearchuk.org/about-cancer/prostate-cancer/treatment/high-intensity-focal-ultrasound-hifu
  3. Hormone Therapy for Prostate Cancer - National Cancer Institute - https://www.cancer.gov/types/prostate/prostate-hormone-therapy-fact-sheet